12 Best Travel Backpacks for South America in 2025

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12 Best Travel Backpacks for South America in 2025


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The best travel backpacks for South America offer durability, security, and ample storage to keep your belongings safe and organized during your adventure. We’ve reviewed the best of the best to help you find the perfect match for the unique landscapes and adventures that South America has to offer!

Heading to South America? Awesome choice! But let’s talk backpacks—because picking the right one can make all the difference. Whether you’re planning to scale the Andes, cruise through the Amazon, or just hop from city to bustling city, you need a pack that’s up for anything.

We’ve done the heavy lifting for you and sifted through tons of options to bring you the 12 best travel backpacks perfect for South America. Are you ready to see which backpacks made the cut? Let’s jump right in and find your perfect travel buddy for your South American adventure.

The best travel backpacks for South America right now

How to Choose the Best Backpack for South America

When gearing up for South America, choosing the perfect backpack can be a real game-changer for your trip. Here’s the lowdown on picking a pack that’s as ready for adventure as you are.

  • Durability is Key: First up, South America can be tough on gear, with everything from mountain treks to city explorations. You’ll want a backpack that’s made to last. Look for strong materials that can take a beating without falling apart.
  • Comfort Comes First: You’ll be carrying this pack a lot, so make sure it feels good on your back. A padded back panel and comfy shoulder straps are must-haves. It’s even better if you can adjust it to fit your body perfectly.
  • Size Matters: Think about what you’ll be doing. A 40-60 liter backpack is ideal for most travelers. It’s big enough to fit everything but still small enough to handle easily on buses and crowded streets.
  • Weather-Proofing: From tropical rain to Andean snow, the weather can change in a heartbeat. A water-resistant backpack, or one with a rain cover, will keep your stuff dry no matter what Mother Nature throws at you.
  • Security Features: Lastly, with bustling markets and busy bus terminals, a backpack with lockable zippers and hidden pockets will keep your valuables safe from sneaky hands.

Picking the right backpack is all about balancing what you need with where you’re going. Get this choice right, and your trip will be a lot smoother!

Top Rated Travel Backpacks For South America

Our roundup of the best backpacks for South America ensures you have a reliable, comfortable, and functional companion for everything from city explorations to wilderness treks. Discover which options offer the durability, comfort, and features suited for the diverse landscapes of this continent!

Not enough time to read? Here’s a rundown of the best travel backpacks for South America:

  • Most Durable: Osprey Aether Plus 70L
  • Best for Comfort: Osprey Atmos 65
  • Best for City Hopping: Osprey Farpoint 40
  • Best for Digital Nomads: Tortuga Laptop Backpack
  • Most Versatile: Tropicfeel Shell
  • Best for Hiking: Osprey Aura 50L
  • Best Budget Pick: Cotopaxi Allpa 42
  • Best for Long Treks: Osprey Airscape UNLTD
  • Best Lightweight Option: Osprey Ozone 38L

1. Osprey Farpoint Trek 55

Packing for South America? Meet the Osprey Farpoint Trek 55. This backpack’s got your back, whether you’re trekking through the Amazon or chilling in Chile. Its trampoline-style back panel means carrying comfort all day long. And guess what? It’s adjustable, fitting four different heights. So whether you’re tall or short, this pack suits everyone.

Rain? No problem. The included rain cover keeps everything dry. If you’re heading on a long hike, just strap a tent or sleeping bag to the external clips. Though it’s roomy enough for all your gear, it’s still sleek enough for city hops.

Here’s the cool part: it’s hydration system-compatible. Stay hydrated without stopping to rummage for a water bottle. While it’s a tad too big for carry-on, the extra space means you can bring back some souvenirs. If you’re looking for good travel backpacks that handle South America’s diverse climates and activities, the Osprey Farpoint Trek 55 should be on your list.

The Osprey Farpoint Trek 55 is one of the best travel backpacks for South America.The Osprey Farpoint Trek 55 is one of the best travel backpacks for South America.
Meet the Osprey Farpoint Trek 55, a versatile and adjustable backpack for any adventure.

2. Cotopaxi Allpa 42

Meet the Cotopaxi Allpa 42, a vibrant and sturdy companion for your South American escapades. This pack opens clamshell-style for easy access, no matter where you are. It’s carry-on compliant, so you can zip through airports with ease. The integrated rain cover? It’s a lifesaver during sudden downpours in the Andes or the steamy Amazon.

Its robust build can handle the rigors of rough terrain while keeping your gear organized and accessible. Inside, you’ll find compartments for everything. There’s even a special spot for your laptop, making it a great pick for digital nomads.

Adjustable sternum straps and a supportive hip belt make carrying heavy loads more comfortable. Plus, it’s made from tough, sustainable materials—good for you and the planet.

In your search for great travel backpacks, the Cotopaxi Allpa 42 stands out with its practical design and eye-catching style. It’s perfect for anyone ready to tackle the diverse landscapes of South America.

The Cotopaxi Allpa 42 is a durable, vibrant backpack with clamshell access and a rain cover.The Cotopaxi Allpa 42 is a durable, vibrant backpack with clamshell access and a rain cover.
The Cotopaxi Allpa 42 is a durable, vibrant backpack with clamshell access and a rain cover.

3. Salkan Backpacker

Check out the Salkan Backpacker, one of the cool travel backpacks tailor-made for the South American trekker. This 2-in-1 system packs both a main backpack and a detachable daypack. It’s like getting two bags for the price of one! Designed for the modern adventurer, the Salkan Backpacker sports a stylish look with a durable polyester that mimics canvas. It’s rugged yet chic, ready for both city sights and country trails.

The main compartment is accessible from the top and side, making it easy to grab what you need without digging. It features plenty of pockets and even a laptop sleeve, ensuring your essentials are always handy. Customizable patches let you add a personal touch to your pack, making it uniquely yours.

Comfort isn’t compromised, thanks to a highly padded waist strap and an adjustable back panel. It’s a breeze to carry, even when fully loaded. And don’t forget the integrated rain cover for those unpredictable South American showers.

The Salkan Backpacker is a stylish 2-in-1 travel backpack with a main pack and detachable daypacK.The Salkan Backpacker is a stylish 2-in-1 travel backpack with a main pack and detachable daypacK.
The Salkan Backpacker is a stylish 2-in-1 travel backpack with a main pack and detachable daypack.

4. Osprey Atmos 65

If you’re scouting for top-rated travel backpacks, the Osprey Atmos 65 should definitely be on your radar. This pack is built to handle the tough, varied climates of South America. It’s designed for those who carry heavy loads but hate feeling weighed down. Its Anti-Gravity suspension system makes it feel lighter than it really is. That’s comfort right there!

The Osprey Atmos 65 isn’t shy on space either. It has a dedicated lower compartment for sleeping bags or tents, making it ideal for multi-day treks in Patagonia or the Andes. With top and side access, grabbing your gear on the go is a breeze. Plus, the integrated raincover keeps everything dry, no matter the weather.

This pack also comes with a trekking pole attachment point, which is perfect for hikes to Machu Picchu or navigating the rugged terrain of Torres del Paine. And for hydration on the move, there’s a handy space for your water reservoir.

The Osprey Atmos 65 is a lightweight, comfortable backpack for heavy loads and tough climates.The Osprey Atmos 65 is a lightweight, comfortable backpack for heavy loads and tough climates.
The Osprey Atmos 65 is a lightweight, comfortable backpack for heavy loads and tough climates.

5. Nomatic 40L Travel Bag

Meet the Nomatic 40L Travel Bag, your new go-to for jetting off to South America. This bag is a standout for its sleek design and serious organizational prowess. Engineered for the savvy traveler, it offers a unique compartment system that keeps your belongings tidy and easily accessible, which is perfect for those constantly on the move.

What makes this one of the best traveling backpacks? It’s all in the details. The Nomatic 40L features a durable, water-resistant build, ensuring your gear stays dry in any weather. It has a dedicated laptop and tablet sleeve, keeping your tech safe and secure. Plus, its size makes it ideal for hopping on buses or stowing in overhead bins on planes.

With clever features like a built-in laundry bag and RFID-safe pocket, this backpack is more than just storage—it’s a tool that enhances every part of your journey across South America. It’s designed to be as dynamic and adaptable as the travelers who wear it.

The Nomatic 40L Travel Bag is a sleek, organized companion for savvy travelers.The Nomatic 40L Travel Bag is a sleek, organized companion for savvy travelers.
The Nomatic 40L Travel Bag is a sleek, organized companion for savvy travelers.

6. Tropicfeel Shell

Explore South America with the Tropicfeel Shell, a backpack that’s as versatile as it is smart. It starts as a compact 22-liter pack but expands to 40 liters with the help of a clever wardrobe system. This means you can adjust its size based on your needs, whether it’s a weekend getaway or a longer expedition. It’s also water and weather-resistant, perfect for the continent’s diverse climates.

Tailored as one of the leading travel backpacks for men, the Tropicfeel Shell features an ergonomic design that ensures comfort even when fully packed. The backpack is equipped with an integrated weight balance system that distributes the load evenly. This makes it easier to carry heavy loads without straining your back.

Additionally, its organized storage system allows quick access to all your essentials, ensuring that you’re always ready for the next adventure. The bag’s outer shell is made from recycled materials, making it a great choice for eco-conscious travelers.

Discover South America with the water-resistant Tropicfeel Shell, expanding from 22 to 40 liters.Discover South America with the water-resistant Tropicfeel Shell, expanding from 22 to 40 liters.
Discover South America with the water-resistant Tropicfeel Shell, expanding from 22 to 40 liters.

7. Osprey Aether Plus 70L

The Osprey Aether Plus 70L is a powerhouse, built for those who take their South American travels seriously. This bag can handle long treks across Patagonia or backpacking through the Andes. Its 70-liter capacity means you can pack everything you need for extended adventures. Durability? Check. It’s made with high-tenacity nylon that withstands the toughest conditions.

This is a nice backpack for travel because it adapts to different body shapes and sizes with a customizable fit. The integrated AirScape back panel keeps you cool as you hike through humid rainforests or sun-drenched landscapes. It’s also hydration compatible, so you can easily sip water without stopping to unpack.

For organization, the Aether Plus 70L has multiple compartments and pockets, including a sleeping bag compartment. It’s all about making life on the road easier. With its sturdy build and thoughtful design, this backpack is a true travel partner.

The Osprey Aether Plus 70L is a durable backpack for long South American treks.The Osprey Aether Plus 70L is a durable backpack for long South American treks.
The Osprey Aether Plus 70L is a durable backpack for long South American treks.

8. Osprey Aura 50L

Step into your South American adventure with the Osprey Aura 50L. This backpack is designed to handle the varied terrain of the continent, from Colombia’s coffee regions to the salt flats of Bolivia. With 50 liters of capacity, it’s sized right for everything you need without weighing you down. The high-tenacity recycled nylon ensures it can take a beating on buses, boats, and trails.

Its Anti-Gravity suspension system is a standout, distributing weight so evenly you might forget you’re carrying a packed bag. Plus, with easy access to compartments and an integrated raincover, it’s ready for any weather you encounter.

Specifically, this is an excellent travel backpack for women. It’s tailored to fit the female form, with an adjustable harness and hip belt designed for comfort. Whether you’re navigating urban centers or remote paths, it provides the support you need.

The Osprey Aura 50L is a durable, 50-liter backpack for South American adventures.The Osprey Aura 50L is a durable, 50-liter backpack for South American adventures.
The Osprey Aura 50L is a durable, 50-liter backpack for South American adventures.

9. Osprey Airscape UNLTD

The Osprey Airscape UNLTD is among the top rated travel backpacks for a good reason. It’s built to endure the challenging environments of South America, from the dense jungles to rugged mountain trails. This backpack thrives on functionality, with a 68-liter capacity that fits all your essentials and more. The cutting-edge, 3D-printed lumbar support offers unmatched comfort, crucial for long days of trekking.

It features an AirScape back panel for excellent ventilation, a must in the humid and hot regions. The pack’s design allows for an even distribution of weight, making heavy loads feel lighter. Additionally, its durability is top-notch, crafted from high-quality materials that resist wear and tear.

This pack is also designed with practicality in mind. It includes a removable top lid that converts to a daypack, ideal for shorter excursions away from your base camp.

The Osprey Airscape UNLTD is a 68-liter backpack built for comfort in South America's rugged terrain.The Osprey Airscape UNLTD is a 68-liter backpack built for comfort in South America's rugged terrain.
The Osprey Airscape UNLTD is a 68-liter backpack built for comfort in South America’s rugged terrain.

10. Osprey Farpoint 40

The Osprey Farpoint 40 is the ultimate travel buddy for your South American tour. This backpack is designed for ease and efficiency on the move. Its 40-liter capacity is perfect for those who like to pack light but need enough space for the essentials. Made from tough, recycled materials, it’s durable enough to handle the hustle of urban adventures and rough rural treks.

Its compact size means you can zip through airports and hop on buses without the hassle of checking in your bag. Plus, it has a stowaway back panel, harness, and hip belt, making it versatile for any travel scenario. You get the comfort of a backpack with the convenience of a suitcase.

Lockable compartments and dual front mesh pockets provide secure, easy access to your items. Whether you’re navigating the busy streets of Rio or exploring the ancient ruins of Peru, the Osprey Farpoint 40 ensures your journey is smooth.

The Osprey Farpoint 40 is a durable 40-liter backpack designed for efficient travel in South America.The Osprey Farpoint 40 is a durable 40-liter backpack designed for efficient travel in South America.
The Osprey Farpoint 40 is a durable 40-liter backpack designed for efficient travel in South America.

11. Tortuga Laptop Backpack

The Tortuga Laptop Backpack is your go-to for tech-savvy travel in South America. This pack excels in urban environments and is perfect for those who work while they wander. At 24 liters, it’s compact yet spacious enough to fit all your digital essentials and daily gear.

It has a spacious main compartment that opens wide for easy packing. There’s a dedicated electronics section with padded sleeves for your laptop and tablet, along with multiple pockets, including expandable water bottle holders, a front pocket, and a quick-access top pocket with a key clip.

Made from waterproof sailcloth, this backpack keeps your belongings dry. It features cushioned shoulder straps, an EVA molded back panel, and an adjustable sternum strap for comfort. Lockable zippers and a luggage handle pass-through sleeve add extra security and convenience.

Ideal for travel and daily use, this backpack fits under airplane seats and offers organized storage for tech gear and essentials. Its thoughtful design and durable materials ensure both functionality and style.

For comfort, the Tortuga Setout features padded shoulder straps and a breathable back panel. This makes it easy to carry, even when loaded with all your tech. The sleek design also blends in well, preventing you from standing out as a tourist.

The Tortuga Laptop Backpack is a 24-liter pack perfect for tech-savvy travel in South America.The Tortuga Laptop Backpack is a 24-liter pack perfect for tech-savvy travel in South America.
The Tortuga Laptop Backpack is a 24-liter pack perfect for tech-savvy travel in South America.

12. Osprey Ozone 38L

Dive into your South American adventure with the Osprey Ozone 38L, one of the best backpacking backpacks for travel. This bag is a champion of versatility, making it perfect for those hopping between cities and exploring rugged landscapes. At 38 liters, it strikes the ideal balance between portability and storage capacity.

It features a high-clearance, four-wheel chassis and a reimagined aluminum frame for smooth rolling. Integrated top and bottom handles make lifting easy, while the buttonless monopole trolley handle enhances maneuverability.

This carry-on includes a 16″ laptop sleeve for convenient access during security checks, coated zippers for water resistance, and a Travel Sentry ID to help recover lost luggage. Made from recycled materials, it combines sustainability with functionality.

With its sleek design and thoughtful features, this carry-on ensures a hassle-free travel experience. Ideal for both business and leisure travelers, it fits overhead compartments and offers organized storage for essentials.

 The Tortuga Laptop Backpack is one of the best travel backpacks for South America. The Tortuga Laptop Backpack is one of the best travel backpacks for South America.
The Osprey Ozone 38L is a versatile 38-liter backpack perfect for South American adventures.

Frequently Asked Questions About Gearing Up for South America

Check out our FAQ section to find answers about cool backpacks that will make your trip even better.

How do I keep my backpack safe from theft in South America?

Opt for a backpack with security features like lockable zippers and hidden pockets. Many travel backpacks come equipped with RFID-blocking materials to protect your cards and passports. When traveling, it’s also smart to use luggage locks and to keep your backpack in sight or secure it to immovable objects when sitting down.

Is a backpack better than a suitcase for traveling in South America?

In many cases, yes. Backpacks offer more flexibility and are easier to carry on various terrains and through crowded areas, which is typical in South America. They are also better for areas where you might find uneven paths or cobblestone streets, unlike suitcases which can be cumbersome to roll.

Can you recommend a backpack that is good for both hiking and city touring in South America?

Certainly! Look for a backpack that is around 40 to 50 liters with features suitable for both city touring and hiking. It should be robust enough to handle outdoor wear and tear but sleek enough not to be cumbersome in urban environments. Features like a padded laptop compartment and a hydration reservoir compatibility are also beneficial for such versatile use. This will come in handy in cities like Bogota and Buenos Aires to nature spots in Patagonia.

Final Thoughts on Choosing the Best Backpack for South America

And there you have it—a rundown of the best backpacks to take on your South American adventure. Whether you’re scaling mountains, exploring ancient ruins, or just soaking in the urban vibes, the right backpack can make your journey smoother and more enjoyable.

Remember, choosing the perfect backpack is all about balancing your needs with the conditions you expect to face. Look for durability, comfort, and functionality, and consider how each feature will help you on your travels.

So, pack up your gear, grab one of these top-notch backpacks, and set out on an unforgettable South American journey. Adventure awaits, and now you’re equipped to meet it head-on.

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